Bibliography on PNI (psychoneuroimmunology)
Bibliographie sur la PNI (psychoneuroimmunologie)
13 Janv 98

1. Ader, R. On the teaching of psychoneuroimmunology [editorial]. Brain Behav Immun 10(4), 315-323. 1996.

Notes: 97197914 Type: EDITORIAL ISSN: 0889-1591 Language: Eng

2. Anderson, J. L. The immune system and major depression. Adv Neuroimmunol 6(2), 119-139. 1996.
Department of Psychiatry, Harvard Medical School, Boston, MA, USA
Notes: This paper reviews research literature on the links between human immune functioning and mood disorders. It summarizes the initial steps of this fledgling research area since its inception in the late 1970s, and outlines a range of studies that are needed to increase our neuroimmunological sophistication. Future investigations will require greater specificity in several interrelated realms of inquiry: diagnostic, epidemiologic, and physiologic. In particular, this paper highlights basic physiological studies needed in both neurophysiology and immunology to provide a foundation for meaningful examination of their interface. Among the areas that require more specific investigation in both immunologic and mood disorders research is that of temporal organization. Just as psychiatric researchers have begun to scrutinize temporal cycles of mood, behavior, and neurophysiology, so too exploration of immune functioning must take into account predictable temporal cycles such as circadian and ultradian rhythms, as they shape responses to unanticipated external perturbations. Clarification of the temporal dimension will add significantly to our analysis of the links between immune functioning and mood disorders. The basic science of psychoneuroimmunology continues to mature, bringing new discoveries and revealing hitherto unknown mechanisms and interactions. This is a field of study in many ways still on the frontier, and explication of the long suspected links between mood disorders and immune functioning continues to beckon Type: JOURNAL ARTICLE Type: REVIEW Type: REVIEW, TUTORIAL ISSN: 0960-5428 Language: Eng

3. Biondi, M. and Zannino, L. G. Psychological stress, neuroimmunomodulation, and susceptibility to infectious diseases in animals and man: a review. Psychother Psychosom 66(1), 3-26. 1997.
Clinica Psichiatrica, University of Rome, La Sapienza, Italy
Notes: This article reviews research on the role of psychological stress, personality, social support and other psychosocial factors in bacterial, viral and parasitic infections. After 100 years of research on man and animals, psychological stress is considered as a potential cofactor in the pathogenesis of infectious disease. Psychological stress seems able to alter the susceptibility of animals and man to infectious agents, influencing the onset, course and outcome of certain infectious pathologies. Many experiments have identified in neuroimmunomodulation the principal mediator of the alterations associated with conditions of stress. The development of psychoneuroimmunology has fostered in-depth study of the complex relationship between psychosocial factors, the central nervous system, the immune system and infectious disease. Although antimicrobial drugs have certainly remained the basis of all anti- infective therapy, this type of study has already led some authors to propose and experiment protocols of psychological intervention or psychoimmunotherapy in pathologies such as tuberculosis, or herpes simplex virus or human immunodeficiency virus infections. The psychoneuroimmunological approach to infectious diseases will probably grow in importance in the future not only in the setting of research in psychosomatic medicine but also in that of clinical microbiology Type: JOURNAL ARTICLE Type: REVIEW Type: REVIEW LITERATURE ISSN: 0033-3190 Language: Eng

4. Coe, R. M. The magic of science and the science of magic: an essay on the process of healing. J Health Soc Behav 38(1), 1-8. 1997.
Department of Community and Family Medicine, Saint Louis University School of Medicine, MO 63104, USA.
Notes: coerm@wpogate.slu.edu The field of medical sociology has developed rapidly in recent years in sophistication of conceptualization and research techniques. Nonetheless, there remains a considerable amount of "unexplained variance" in knowledge about health and illness behaviors. This paper asserts that to grow further, medical sociology should become more interdisciplinary in conceptualization and design of research projects. The application of research findings from the field of psychoneuroimmunology to explain the effects of placebos as a form of magic is used as an illustration Type: JOURNAL ARTICLE Type: REVIEW Type: REVIEW, TUTORIAL ISSN: 0022-1465 Language: Eng

5. Huygen, A. C. and Sinnema, G. [Psychological and social aspects of juvenile chronic arthritis] Psychologische en sociale aspecten van juveniele chronische arthritis. Tijdschr.Kindergeneeskd. 59(5), 173-178. 1991.
Psychosociale afd., Universiteitskliniek voor kinderen en jeugdigen, Het Wilhelmina Kinderziekenhuis, Utrecht.
Notes: Juvenile rheumatoid arthritis (JRA) affects the physical, psychological and social development of children and adolescents. Illness characteristics such as visibility, pain and uncertainty may influence the development of independence and social adjustment. Children can suffer from growth deficiencies, school problems, social isolation, sometimes psychopathology. International research does not yield consensus on the incidence of psychopathology in chronically ill children. The psychosocial effects of the illness are partly determined by the ways the child and the family react to the illness and its physical consequences. The functioning of child and family ultimately depends upon the balance between burdens and strengths. Reciprocal influences between illness and daily living can be understood through modern psycho-neuroimmunologic theories. These concepts ask for a multidisciplinary team-approach for suitable, individualized care

6. Kiecolt-Glaser, J. K., Cacioppo, J. T., Malarkey, W. B., and Glaser, R. Acute psychological stressors and short-term immune changes: what, why, for whom, and to what extent? [editorial; comment]. Psychosom.Med. 54(6), 680-685. 1992.

Notes: 93087715 (UNITED STATES) 0033-3174 ENGLISH 9303 INDEX MEDICUS

7. Kiecolt-Glaser, J. K. and Glaser, R. Psychoneuroimmunology: can psychological interventions modulate immunity? J.Consult.Clin.Psychol. 60(4), 569-575. 1992.
Department of Psychiatry, Ohio State University College of Medicine, Columbus 43210 (UNITED STATES)
Notes: There is ample evidence from human and animal studies demonstrating the downward modulation of immune function concomitant with a variety of stressors. As a consequence, the possible enhancement of immune function by behavioral strategies has generated considerable interest. Researchers have used a number of diverse strategies to modulate immune function, including relaxation, hypnosis, exercise, classical conditioning, self-disclosure, exposure to a phobic stressor to enhance perceived coping self-efficacy, and cognitive-behavioral interventions, and these interventions have generally produced positive changes. Although it is not yet clear to what extent these positive immunological changes translate into any concrete improvements in relevant aspects of health, that is, alterations in the incidence, severity, or duration of infectious or malignant disease, the preliminary evidence is promising

8. Moynihan, J. A. and Ader, R. Psychoneuroimmunology: animal models of disease. Psychosom.Med. 58(6), 546-598. 1996.
Center for Psychoneuroimmunology Research, University of Rochester School of Medicine and Dentistry, New York, USA
Notes: OBJECTIVE: Psychoneuroimmunology, which investigates the bidirectional communication between the central nervous system and the immune system, has been greatly advanced by the use of animal models. The objective of this paper is to describe animal models of disease that can or might be utilized to elucidate neural-immune interactions that alter pathogenesis. METHODS: This paper reviews animal studies that have demonstrated a link among the brain, behavior, immunity, and disease, highlighting models in which the potential contribution of CNS-immune interactions has not yet been explored. RESULTS: Animal studies allow for careful control of environmental stimuli, genetic background, and immunological challenge. As such, they are an important component of psychoneuroimmunology research. Models in which one might study the role of psychosocial factors in immunologically mediated disease processes, as in the case of other pathophysiologic processes, profit from an ability to manipulate both stressful events and the magnitude of the challenge to the immune system. CONCLUSIONS: Animal studies in psychoneuroimmunology highlight the complexity of the interactions among behavior, the brain, the immune system, and pathogen. The genetic background of the animal (both in terms of central nervous and immune system responses), its previous history, the nature of the stressor, the nature of the pathogen and the type of immune response generated are some of the interacting factors that determine the magnitude and direction of stress-induced changes in disease outcome Type: JOURNAL ARTICLE Type: REVIEW Type: REVIEW, ACADEMIC ISSN: 0033-3174 Language: Eng

9. Rogers, M. P. and Fozdar, M. Psychoneuroimmunology of autoimmune disorders. Adv Neuroimmunol 6(2), 169-237. 1996.
Department of Psychiatry, Harvard Medical School, Boston, MA 02115, USA
Notes: The interactions between the immune system and psychological states are both intricate and intriguing. Research at a molecular level has thrown considerable light on the previously ill-defined area of psychoneuroimmunology. In this report, we explore the psychoneuroimmunology of autoimmune disorders, particularly rheumatoid arthritis and lupus erythematosus. Animal models of these diseases have provided a particularly useful window on complex psychoneuroimmunological interactions. Observations about the effect of stress on the onset and course of autoimmune disorders has added to our understanding of psychoneuroimmunological interactions. These interactions are bi- directional, as reflected in the autoimmune-mediated neuropsychiatric manifestations of systemic lupus. Exploring the role of various neurotransmitters and neuromodulators in the stress response may have important therapeutic implications for autoimmune disorders Type: JOURNAL ARTICLE Type: REVIEW Type: REVIEW, TUTORIAL ISSN: 0960-5428 Language: Eng

10. Rotenberg, V. S., Sirota, P., and Elizur, A. Psychoneuroimmunology: searching for the main deteriorating psychobehavioral factor. Genet Soc Gen Psychol Monogr 122(3), 329-366. 1996.
Abarbanel Mental Health Center, Bat Yam, Israel
Notes: Psychoneuroimmunology has become an independent science with a broad experimental basis. However, its theoretical basis is still very vague and ambiguous. There are many contradictions in the experimental data that have not been integrated into a united conception, and some accepted paradigms that remain doubtful. The present critical review suggests a conceptual approach to the problem based on the proposition of two opposite types of behavior (search activity and renunciation of search) with attempts to integrate experimental results by avoiding contradiction. The analysis of the literary data confirms that every behavior that includes search activity prevents psychoimmunological disorders, whereas renunciation of search displays a general predisposition to such disorders. Such an approach makes possible new solutions of paradoxes and broadens the possible interpretations of the alteration of immune functions in depression, anxiety, and stressful events Type: JOURNAL ARTICLE Type: REVIEW Type: REVIEW, TUTORIAL ISSN: 8756-7547 Language: Eng

11. Vishwanath, R. The psychoneuroimmunological system: a recently evolved networking organ system. Med Hypotheses 47(4), 265-208. 1996.
Oncology Division, Dabur Research Foundation, Uttar Pradesh, India
Notes: The phenomenon of psychological influences on immune activity and general physiology has generated a great deal of interest in the last decade. Several theories have been proposed to understand the evolution and the nature of this bi-directional coOncmmunication and/or influence. It is shown that the existing theories do not fully explain most phenomena associated with this communication. A theory--the networking organ theory--is also suggested that could resolve the issue. The information obtained from recent studies on evolutionary history and the fossil record have been used as the basis for understanding the phenomenon of psychoneuroimmunology. In essence, we are not looking at the unification of the mind and the body, but at a recently evolved system that lends sophistication to the existing connection between the mind and the body Type: JOURNAL ARTICLE ISSN: 0306-9877 Language: Eng

12. Weiss, D. W., Hirt, R., Tarcic, N., Berzon, Y., Ben-Zur, H., Breznitz, S., Glaser, B., Grover, N. B., Baras, M., and OqDorisio, T. M. Studies in psychoneuroimmunology: psychological, immunological, and neuroendocrinological parameters in Israeli civilians during and after a period of Scud missile attacks. Behav Med 22(1), 5-14. 1996.
Lautenberg Centre for General and Tumor Immunology at Hebrew University-Hadassah Medical School, Jerusalem, Israel
Notes: Twenty-two male volunteers in Jerusalem were subjected to a battery of psychological tests at the height of the Iraqi Scud missile attacks on Israeli cities during the 1991 Persian Gulf War and again after the cessation of hostilities. Venous blood samples were taken at each time point. The separated mononuclear cells and plasma were cryopreserved, and a spectrum of immunological and neuroendocrine assays were performed on the preserved samples. Psychological testing indicated levels of anxiety were higher during the war than they were after the war ended, and both anxiety and anger during the hostilities were significantly elevated in comparison with prewar data. During the war, specific war-related pressures were greater than everyday pressures, and problem-focused coping was more evident than emotion-focused coping. Natural-killer cell activity and cell- mediated lympholysis were significantly elevated during the war, as were plasma levels of adrenocorticotrophic hormone, neurotensin, and substance P. The only biological test parameter found to be reduced during the war period was mononuclear cell thymidine incorporated in nonstimulated cultures Type: JOURNAL ARTICLE ISSN: 0896-4289 Language: Eng

13. Zeller, J. M., McCain, N. L., and Swanson, B. Psychoneuroimmunology: an emerging framework for nursing research. J.Adv.Nurs. 23(4), 657-664. 1996.
Department of Medical Nursing, Rush-Presbyterian-St Luke's Medical Center, Chicago, Illinois 60612, USA
Notes: Psychoneuroimmunology (PNI) is concerned with the mechanisms of bidirectional communication between the neuroendocrine and immune systems. Investigators in other disciplines have used this framework to guide the examination of possible relationships between behavioural factors and the progression of immunologically mediated illnesses and to evaluate the role of immune products in central nervous system disturbances. Nurse scientists have an opportunity to make unique contributions to the growing field of PNI. Unlike basic science research, which has as its goal the generation of fundamental knowledge concerning biological or behavioural processes, nursing research is driven by the need to promote excellence in nursing science as a guide for nursing practice. Although a few nurse scientists have conducted PNI research to date, additional studies are needed to generate new knowledge concerning mind-body interactions in health and illness and to develop strategies that promote mental and physical well-being in persons at risk for immune dysfunction. This paper highlights the few recently conducted nursing studies grounded in a PNI framework to illustrate the utility of PNI in advancing nursing science Type: JOURNAL ARTICLE Type: REVIEW Type: REVIEW, TUTORIAL ISSN: 0309-2402 Language: Eng